Thursday, 8 April 2010

The FAB (old) classification of MDS, from Wikipedia

MDS is classified according to bone marrow findings:
  • RA = refractive anaemia
    Myeloblasts less than 5%.
    Sideroblasts less than 15%.
    Pathology mostly confined to erythroid precursors.
  • RARS = RA with ringed sideroblasts
    Myeloblasts less than 5%.
    Sideroblasts more than 15%.
  • RAEB = RA with excess blasts
    Myeloblasts 5-20%.
  • RAEBt = RAEB in transformation
    Myeloblasts 21-30% (more than 30% blasts = AML, by definition).
  • CMML = chronic myelomonocytic leukaemia
    5-20% blasts + monocytes > 1000x109cells/µL.
In the newer WHO classification CMML is no longer considered a MDS, but an overlap between MDS and MPD.

No comments:

Post a Comment